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Symbol
Name
ID
Upf2
UPF2 regulator of nonsense transcripts homolog (yeast)
MGI:2449307
Phenotype annotations related to hematopoietic system
Darker colors indicate more annotations

Mouse Phenotypes
decreased T cell proliferation
thymus hypoplasia
abnormal T cell receptor beta chain V(D)J recombination
decreased double-positive T cell number
anemia
abnormal bone marrow cell morphology/development
abnormal common lymphocyte progenitor cell morphology
low mean erythrocyte cell number
decreased hematocrit
decreased hemoglobin content
decreased granulocyte number
abnormal B cell number
decreased CD4-positive, alpha-beta T cell number
decreased CD8-positive, alpha-beta T cell number
decreased hematopoietic stem cell number
Availability Mouse Genotype
Upf2tm1Btp/Upf2tm1Btp
Tg(Mx1-cre)1Cgn/0  (conditional)
Tg(Lck-cre)548Jxm/?
Upf2tm1Btp/Upf2tm1Btp  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory